This is Toroko “old” and “new”.
This is sweet and interesting to look at. The Cave Story will be ported to the Wii and the characters will be slightly powered up. As you can see on the picture, the number of pixel doubled, in order to enhance the detail level. The sweet thing is, that, according to Infendo, you will have the option to play the new or the original pixelset of the characters at the Wii version of Cave Story. Thumbs up again for Nintendo. Get all details at the Nicalis-blog.
Generally spoken: Doubling the number of pixels is a very interesting technique to design sprites and characters I think. Even to use it systematically. Start with a white square. 
